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  • Takuya Kitamoto, Aya Kitamoto, +11 authors Kikuko Hotta
  • Biology, Medicine
  • Human Genetics
  • 2013 (First Publication: 28 March 2013)
  • We examined the genetic background of nonalcoholic fatty liver disease (NAFLD) in the Japanese population, by performing a genome-wide association study (GWAS). For GWAS, 392 Japanese NAFLD subjectsExpand
  • Takuya Kitamoto, Aya Kitamoto, +7 authors Kikuko Hotta
  • Medicine
  • Journal of hepatology
  • 2015 (First Publication: 1 August 2015)
  • BACKGROUND & AIMS The pathogenesis of non-alcoholic fatty liver disease (NAFLD) is affected by epigenetic factors as well as by genetic variation. METHODS We performed targeted-bisulfite sequencingExpand
  • Kikuko Hotta, Aya Kitamoto, +33 authors Akihiro Sekine
  • Medicine, Biology
  • Journal of Human Genetics
  • 2012 (First Publication: 1 May 2012)
  • Visceral fat accumulation has an important role in the development of several metabolic disorders, such as type 2 diabetes, dyslipidemia and hypertension. New genetic loci that contribute to theExpand
  • Takuya Kitamoto, Aya Kitamoto, +9 authors Kikuko Hotta
  • Biology, Medicine
  • Journal of Human Genetics
  • 2014 (First Publication: 1 May 2014)
  • The genomic regions containing PNPLA3, SAMM50 and PARVB are susceptibility loci for the development and progression of nonalcoholic fatty liver disease (NAFLD). In order to search for all commonExpand