Ayşen Akıncı

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To evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of(More)
Systemic lupus erythematosus (SLE) is a multisystem chronic inflammatory disease with a broad spectrum of clinical and serological manifestations. Although articular involvement is known in SLE, articular cartilage has not been studied before. Therefore, in this study, we have evaluated the femoral cartilage by using ultrasonography. Twenty-nine SLE(More)
Recently, osteoporosis has attracted concern among physicians treating patients with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS). Many confounding factors are assumed to play a role in its pathogenesis. The discussion has increased dramatically since the introduction of highly active antiretroviral therapy (HAART), and, in(More)
AIM To explore the relationship among clinical, radiological and ultrasonographical findings in knee osteoarthritis (OA). METHOD Sixty-one patients (122 knees) with knee OA were enrolled. Patients' knees were classified into two groups according to symptom severity. Group I consisted of 61 more symptomatic knees and Group II comprised 61 less symptomatic(More)
OBJECTIVES To investigate the relationship between enthesitis and disease activity, functional status, fatigue, joint mobility, radiological damage, laboratory parameter and quality of life in patients with ankylosing spondylitis (AS). METHODS A total of 421 patients with AS (323 male and 98 female) who were included in the Turkish League Against(More)
A 63-year-old man with complaints of joint pain and ankle swelling was evaluated. The arthralgias he described were mainly in the knees, elbows, and shoulders. Accompanying swelling and erythema in his left ankle and left second metacarpophalangeal (MCP) joint had recently ensued. His past history revealed acromegaly, somatotropinectomy, and radiotherapy.(More)
Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis(RA). The purpose of this study was to evaluate serum concentrations of NO in patients(More)
A 20-year-old man with the complaints of malaise, fever, and tooth gum bleeding presented at a hospital. He was found to have generalized lymphadenopathy, thrombocytopenia, and leukocytosis. Ensuing bone marrow biopsy led to a diagnosis of acute lymphoblastic leukemia (ALL). He also had a sense of "facial stretching" and difficulty during eating. After(More)
Etanercept and adalimumab are first line therapies for the treatment of inflammatory and autoimmune diseases. However, local and systemic hypersensitivity reactions preclude their use in sensitized patients. Immune-mediated adverse reactions to etanercept and adalimumab reported in the literature include injection site reactions (ISRs) and immediate(More)
To the editor, In the year 2000, a 36-year-old lady was seen in our internal medicine department with the complaints of mucoid and bloody diarrhea for the previous 2 weeks. She also reported abdominal discomfort accompanying her symptoms. Her frequency of defecation was allegedly about 7–10 times daily and she never had fever during that period. She denied(More)