Axel Scherer

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PURPOSE To establish quantitative standards for age-related changes in diffusion restriction of cerebral white matter in healthy children and to compare data with results in children with white matter diseases. MATERIALS AND METHODS Diffusion-weighted magnetic resonance (MR) imaging was performed in 44 children (age range, 7 days to 7.5 years) without(More)
To evaluate high-resolution multi-pinhole single photon emission computed tomography (MPH-SPECT) for the detection of bony alterations in early rheumatoid arthritis (ERA), early osteoarthritis (EOA) of the fingers and healthy controls. The clinically dominant hands of 27 patients (13 ERA, nine EOA, five healthy controls) were examined by MPH-SPECT and bone(More)
PURPOSE To evaluate non-enhanced 3D MR angiography using turbo spin echo (TSE) imaging with non-selective refocusing pulses (NATIVE SPACE MRA) for the visualization of the arteries of the lower extremity. MATERIALS AND METHODS Three-station imaging (iliac arteries, femoral arteries, arteries of the lower leg) was performed in 8 healthy volunteers and 3(More)
18F-fluorodeoxyglucose PET (18F-FDG PET) is highly sensitive to inflammatory changes within the synovial tissue in rheumatoid arthritis (RA). However, the highest spatial resolution for soft tissue can be achieved with MRI. Here, we report on the first true hybrid PET–MRI examination of the hand in early RA exploiting the advantages of both modalities.(More)
Conventional radiography is still regarded the gold standard for imaging techniques in rheumatoid arthritis (RA). It is a very important tool for the diagnosis, the differential diagnosis, and the evaluation of the course and prognosis of the disease. Special advantages of conventional radiography are the worldwide availability and experience with the(More)
. Since 1991, enzyme replacement therapy (ERT) has been available for patients with Gaucher disease in Germany. The aim of this study was to analyse the MR pattern of bone marrow involvement and response to ERT in Gaucher disease type I. . Thirty patients with Gaucher disease type I had MRI examinations prior to initiation of ERT with(More)
BACKGROUND Ventilation in the prone position is carried out for improvement of pulmonary gas exchange in patients with acute respiratory distress syndrome (ARDS). We compared the effects of an incomplete prone position (IPP, 135( degrees )) with a complete prone position (CPP, 180( degrees )) in patients with ARDS. PATIENTS AND METHODS For this trial 59(More)
OBJECTIVE To evaluate alterations of the soft tissues, tendons, and bones as detected by magnetic resonance imaging (MRI) in patients with systemic lupus erythematosus (SLE)-associated arthritis of the finger joints. METHODS Both hands of 14 patients with SLE of various activities and durations and with arthritis and/or deformities of the finger joints(More)
Ziel dieser Studie war es, die Prävalenz und klinische Bedeutung inzidenteller Herzbefunde im nicht EKG-getriggerten Thorax-CT ohne primär kardiale Fragestellung zu evaluieren. Dreihundert nicht EKG-getriggerte Thorax-CT-Untersuchungen wurden retrospektiv bzgl. inzidenteller Herzbefunde analysiert. Die klinische Bedeutung wurde von einem Kardiologen(More)
BACKGROUND Pertinent reportable cardiac findings on non-electrocardiography (ECG)-gated chest CT examinations have become easier to detect given recent advancements in multidetector CT technology. However, those findings are easily overlooked on routine chest CT without ECG gating given residual inherent cardiac motion artifact and non-cardiac indications.(More)