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Borg’s rating of perceived exertion (RPE) is a widely used psycho-physical tool to assess subjective perception of effort during exercise. We evaluated the association between Borg’s RPE and physiological exercise parameters in a very large population. In this cohort study, 2,560 Caucasian men and women [median age 28 (IQR 17–44) years] completed(More)
INTRODUCTION Strenuous exercise induces significant increases in cardiac biomarkers. However, it is still unclear whether this is caused by cardiomyocyte necrosis or secondary mechanisms such as ischemia, cardiac energy deficiency, increased inflammation, or renal dysfunction. METHODS Therefore, we investigated cardiac biomarkers (high-sensitive cardiac(More)
BACKGROUND Interventions aimed at behavior change are increasingly being delivered over the Internet. Although research on intervention effectiveness has been widely conducted, their true public health impact as indicated by reach, effectiveness, and use is unclear. OBJECTIVE The aim of this paper is to (1) review the current literature on online(More)
OBJECTIVE To evaluate the effect of structured vs. non-structured internet-delivered exercise recommendations on aerobic exercise capacity and cardiovascular risk profile in overweight sedentary employees. METHODS 140 employees of an automobile company (11% female, median age 48 years (range 25-60), BMI 29.0 kg/m(2) (25.0-34.8)) were randomized in a 3:2(More)
BACKGROUND Correction for body composition is recommended for appropriate interpretation of equivocally altered cardiac dimensions. We sought to investigate the impact of body composition on athletes' heart. METHODS Left ventricular mass (LVM), septal wall thickness (SWT) and end-diastolic diameter (LVEDD) were measured by echocardiography in 1051 elite(More)
BACKGROUND The retinal microcirculation is affected early in the process of atherosclerosis and retinal vessel caliber is an emerging cardiovascular risk factor. Obesity is associated with vascular dysfunction. Here, we investigate the effect of regular exercise on retinal vessel diameters in lean and obese runners. We analyze a possible link to alterations(More)
PURPOSE Strenuous exercise induces significant increases in inflammatory and cardiac biomarkers and transient dysfunction of the left ventricle. It is still unclear whether the electrophysiological correlate of these alterations can also be observed in ECG recordings, which indicate increased vulnerability for arrhythmias. METHODS ECG parameters were(More)
Inactivity is the most widespread health risk factor in modern societies today, causing not only individual health problems but also immense costs for the healthcare systems. This emphasizes the need for improving population-wide impact of activity interventions, with particular attention to cost-effectiveness, scalability, and delivery channels. In this(More)
Using spin-polarized scanning tunneling microscopy performed in a triple axes vector magnet, we show that the magnetic structure of the Fe double layer on W(110) is an inhomogeneous right-rotating cycloidal spin spiral. The magnitude of the Dzyaloshinskii-Moriya vector is extracted from the experimental data using micromagnetic calculations. The result is(More)