Axel M Schoene

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Idiopathic pulmonary arterial hypertension (IPAH) is a pulmonary vasculopathy of unknown aetiology. Dyspnoea, peripheral airway obstruction and inefficient ventilation are common in IPAH. Data on respiratory muscle function are lacking. This prospective single-centre study included 26 female and 11 male patients with IPAH in World Health Organization(More)
RATIONALE Congestive heart failure (CHF) frequently results in remodeling and increased tone of pulmonary resistance vessels. This adaptive response, which aggravates pulmonary hypertension and thus, promotes right ventricular failure, has been attributed to lung endothelial dysfunction. OBJECTIVE We applied real-time fluorescence imaging to identify(More)
The close interaction between heart and lungs has pathophysiological and clinical implications both in cardiac and pulmonary diseases. Some aspects of ventriculo-ventricular relations are illustrated using examples of left heart failure and right heart failure or cor pulmonale. This interaction is mediated either by pulmonary vasculature or directly through(More)
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