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We investigated the effects of dopamine, met-enkephalin and leu-enkephalin on basal and ouabain-stimulated release of oxytocin and vasopressin from isolated neurointermediate lobes. The present study revealed that neurohypophyseal hormone release was not affected by dopamine, neither from lobes of untreated rats nor from those of rats with(More)
In vitro oxytocin (OXT) release from isolated posterior pituitary lobes (PPL) of adult male Wistar rats was measured under basal and K+- stimulated conditions using a specific, sensitive radioimmunoassay. A basal release of 0.95 +/- 0.20 ng OXT/lobe/10 min was estimated in standard Locke's bathing solution. An excess of K+ (56 mmol/l) augmented the OXT(More)
The in vitro release of oxytocin (OXT) from posterior pituitary lobes (PPL) of adult female rats is linked to the stage of the animals' sexual cycles. After incubation in normal Locke's solution (K+ 5,6 mM), the basal OXT release from the PPL of rats on diestrus 1 and estrus amounted to 2.25 +/- 0.53 ng/lobe/10 min (mean +/- S.E.M.) and 4.71 +/- 0.61(More)
It is still controversial which mediators regulate energy provision to activated neural cells, as insulin does in peripheral tissues. Interleukin-1β (IL-1β) may mediate this effect as it can affect glucoregulation, it is overexpressed in the 'healthy' brain during increased neuronal activity, and it supports high-energy demanding processes such as long-term(More)
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