Axel Jakuscheit

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Wuerzburg in the centre of Germany claims to be a cradle of modern orthopaedics. Under the leadership of Johann Georg Heine (1771–1831) the first German orthopaedic hospital, the Carolinum, was established in 1816. Johann Georg Heine’s legacy was continued by his son Joseph (1803–1877) and his nephew Bernhard Heine (1800–1846), before Albert Hoffa(More)
BACKGROUND Immediate postoperative pain could be prevented by the administration of long-lasting analgesics before the end of the anaesthesia. However, to prevent over or underdosing of analgesics under anaesthesia, tools are required to estimate the analgesia-nociception balance. OBJECTIVE We investigated whether the pupillary dilation reflex (PDR) and(More)
OBJECTIVE To reanalyze scoring criteria for automatic detection of nociceptive flexion reflexes (NFRs) in electromyography (EMG) recordings and to improve detection accuracy by accounting for multiple characteristics of the recordings, such as baseline noise level or sampling rate. METHODS Single scoring criteria for the NFR were reanalyzed and validated(More)
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