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  • Axel Abelein, Jan Pieter Abrahams, +5 authors Sebastian Wärmländer
  • Medicine, Chemistry
  • JBIC Journal of Biological Inorganic Chemistry
  • 2014 (First Publication: 1 June 2014)
  • The amyloid β (Aβ) peptides are 39–42 residue-long peptides found in the senile plaques in the brains of Alzheimer’s disease (AD) patients. These peptides self-aggregate in aqueous solution, goingContinue Reading
  • Axel Abelein, Jüri Jarvet, Andreas Barth, Astrid Gräslund, Jens Danielsson
  • Medicine, Chemistry
  • Journal of the American Chemical Society
  • 2016 (First Publication: 23 May 2016)
  • Protein misfolding and formation of cross-β structured amyloid fibrils are linked to many neurodegenerative disorders. Although recently developed quantitative approaches have started to reveal theContinue Reading
  • Sebastian Wärmländer, Ann Tiiman, +5 authors Astrid Gräslund
  • Medicine, Chemistry
  • Chembiochem : a European journal of chemical…
  • 2013 (First Publication: 23 September 2013)
  • Alzheimer's disease is the most common of the protein misfolding ("amyloid") diseases. The deposits in the brains of afflicted patients contain as a major fraction an aggregated insoluble form of theContinue Reading
  • Axel Abelein, Benedetta Bolognesi, Christopher M. Dobson, Astrid Gräslund, Christofer Lendel
  • Medicine, Chemistry
  • Biochemistry
  • 2012 (First Publication: 10 January 2012)
  • The link between many neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, and the aberrant folding and aggregation of proteins has prompted a comprehensive search for smallContinue Reading
  • Axel Abelein, Jørn Døvling Kaspersen, +6 authors Astrid Gräslund
  • Medicine, Chemistry
  • The Journal of Biological Chemistry
  • 2013 (First Publication: 17 June 2013)
  • Background: β-Structured oligomers of the amyloid β peptide are considered neurotoxic and on-pathway to amyloid fibril formation. Results: Surfactant-induced co-aggregated oligomers show dynamicContinue Reading
  • Cecilia Wallin, Yashraj Kulkarni, +11 authors Sebastian Wärmländer
  • Chemistry, Medicine
  • Journal of trace elements in medicine and biology…
  • 2016 (First Publication: 1 December 2016)
  • Growing evidence links neurodegenerative diseases to metal exposure. Aberrant metal ion concentrations have been noted in Alzheimer's disease (AD) brains, yet the role of metals in AD pathogenesisContinue Reading