Avinash Eranki

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Background/introduction Magnetic resonance-guided high intensity focused ultrasound (MR-HIFU) ablation provides a precise, non-invasive treatment for lesions in adults. In children, MRHIFU’s potential remains largely unexplored, though its non-invasive and non-ionizing nature holds promise. Yet, pediatric patients pose challenges affecting treatment: young(More)
Background/introduction Treatment duration as well as time spent on patient positioning imposes limitations on therapeutic use of MRguided High Intensity Focused Ultrasound (MR-HIFU). Reduction of overall treatment time is especially important in potential pediatric applications and in other cases where general anesthesia must be used, due to the risks(More)
Background/introduction MR-guided high-intensity focused ultrasound (MRHIFU) treatments may cause skin heating in the vicinity of the treatment site. Current MR thermometry methods do not provide reliable measurements of skin temperature either during the sonication or during the cooldown periods between sonications. These technical challenges require(More)
BACKGROUND Osteoid osteoma (OO) is a painful bone tumour occurring in children and young adults. Magnetic resonance imaging-guided high intensity focussed ultrasound (MR-HIFU) allows non-invasive treatment without ionising radiation exposure, in contrast to the current standard of care treatment with radiofrequency ablation (RFA). This report describes(More)
When exposed to sufficiently high ultrasound pressures, microbubbles can be generated spontaneously in tissue and undergo inertial cavitation where collapses result in physical effects. These effects range from petechial haemorrhage to complete cellular disruption, termed Histotripsy, depending on ultrasound parameters. This presentation will explore the(More)
OBJECTIVE To evaluate clinical feasibility and safety of magnetic resonance imaging-guided high-intensity focused ultrasound (MR-HIFU) treatment of symptomatic osteoid osteoma and to compare clinical response with standard of care treatment. STUDY DESIGN Nine subjects with radiologically confirmed, symptomatic osteoid osteoma were treated with MR-HIFU in(More)
PURPOSE High intensity focused ultrasound (HIFU) is a non-invasive therapeutic technique that can thermally ablate tumors. Boiling histotripsy (BH) is a HIFU approach that can emulsify tissue in a few milliseconds. Lesion volume and temperature effects for different BH sonication parameters are currently not well characterized. In this work, lesion volume,(More)
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