Avantika Agrawal

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A 3D multiscale view has been developed for medical datasets that are composed of multiple images of very different spatial sizes. The example data consisted of 3 volume images of bone: a 400 mm femur; a 20 mm micro-CT image of trabeculae; and a 0.5 mm nano-CT image of a single trabecula. The images were nested, the nano-CT being inside the micro-CT, which(More)
Protein kinase B (PKB, also known as Akt) belongs to the AGC subfamily of the protein kinase superfamily. Akt1 has been reported as a central player in regulation of metabolism, cell survival, motility, transcription and cell-cycle progression, among the signalling proteins that respond to a large variety of signals. In this study an attempt was made to(More)
Collaborative models (<i>e.g.</i>, wikis) are an increasingly prevalent Web technology. However, the open-access that defines such systems can also be utilized for nefarious purposes. In particular, this paper examines the use of collaborative functionality to add inappropriate hyperlinks to destinations outside the host environment (<i>i.e.</i>, link(More)
3D-QSAR studies on the derivatives of 1-(3,3-diphenylpropyl)-piperidinyl amide and urea as CCR5 receptor antagonists were performed by comparative molecular field analysis (CoMFA) and comparative molecular similarity indices (CoMSIA) methods to rationalize the structural requirements responsible for the inhibitory activity of these compounds. The global(More)
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