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Timely controlled oxygen (O2) delivery is crucial for the developing liver. However, the influence of O2 on intercellular communication during hepatogenesis is unclear. Using a human induced… Continue Reading
Human organoid systems recapitulate in vivo organ architecture yet fail to capture complex pathologies such as inflammation and fibrosis. Here, using 11 different healthy and diseased pluripotent… Continue Reading
Organogenesis is a complex and interconnected process that is orchestrated by multiple boundary tissue interactions1–7. However, it remains unclear how individual, neighbouring components coordinate… Continue Reading