Aurora Melandri

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BACKGROUND In chronic lymphocytic leukemia (CLL), next-generation sequencing (NGS) analysis represents a sensitive, reproducible, and resource-efficient technique for routine screening of gene mutations. METHODS We performed an extensive biologic characterization of newly diagnosed CLL, including NGS analysis of 20 genes frequently mutated in CLL and(More)
Erratum n.b. The error described below was mistakenly carried forward by the production team handling this article, and thus was not the fault of the authors. The original version of this article [1] had a duplication of Fig. 1 in place of where Fig. 2 should have been, resulting in two displays of Fig. 1 and the absence of Fig. 2. The article has now been(More)
We investigated whether karyotype analysis and mutational screening by next generation sequencing could predict outcome in 101 newly diagnosed chronic lymphocytic leukemia patients with high-risk features, as defined by the presence of unmutated IGHV gene and/or 11q22/17p13 deletion by FISH and/or TP53 mutations. Cytogenetic analysis showed favorable(More)
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