Aurélien Mazurie

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BACKGROUND Cellular functions are regulated by complex webs of interactions that might be schematically represented as networks. Two major examples are transcriptional regulatory networks, describing the interactions among transcription factors and their targets, and protein-protein interaction networks. Some patterns, dubbed motifs, have been found to be(More)
Identifying biomarkers that are indicative of a phenotypic state is difficult because of the amount of natural variability which exists in any population. While there are many different algorithms to select biomarkers, previous investigation shows the sensitivity and flexibility of support vector machines (SVM) make them an attractive candidate. Here we(More)
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. An evolutionary and functional assessment of regulatory network motifs <p>Cross-species comparison and functional analysis of over-abundant motifs in an integrated network of yeast transcriptional and protein protein interaction data(More)
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