Auke C Schaefers-Okkens

Learn More
OBJECTIVE To determine if ovariectomy (OVE) is a safe alternative to ovariohysterectomy (OVH) for canine gonadectomy. STUDY DESIGN Literature review. METHODS An on-line bibliographic search in MEDLINE and PubMed was performed in December 2004, covering the period 1969-2004. Relevant studies were compared and evaluated with regard to study design,(More)
During oestrus the plasma progesterone concentration can be used to determine the optimal time for mating in the dog. In this study, the optimal time for mating for 26 bitches was determined by measuring progesterone concentrations with three ELISA test kits and a 125I-radioimmunoassay (125I-RIA). Two observers evaluated the ELISA results simultaneously.(More)
A decline in circulating progesterone concentration plays an important role in the ethiopathogenesis of pseudopregnancy in the bitch. Because growth hormone (GH) and prolactin (PRL) are essential for normal mammogenesis and the secretion of these hormones is influenced by changes in the circulating progesterone concentration, the purpose of this study was(More)
Progesterone exerts its effect by binding to specific progesterone receptors (PR) within the cell. In dogs and cats, no data are available on PR isoforms as found in other species. We therefore investigated the sequence of the PR gene and encoded protein in dogs and cats, the expression of PR isoforms in mammary tissue using Western blots and the presence(More)
Kisspeptin (KP) plays a key role in the regulation of the hypothalamic-pituitary-gonadal axis via the release of GnRH. As normal KP signaling is essential for reproductive function, it could be an interesting new target for therapeutic interventions, e.g., nonsurgical contraception in dogs. The aims of the present study were to investigate the effect of(More)
To point out which antibiotics and NSAIDs are safe to use during pregnancy of the dog and which are not, a simple system for classification has been developed for veterinarians. To find out more information about what drugs and during what stage of pregnancy veterinarians prescribe, a random survey was carried out among veterinarians who work primarily with(More)