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From the results of this study of the action of immune sera on pneumococcus infection it is evident that immune sera vary greatly in their curative value. Immune sera possess protective action, but protective action is not necessarily indicative of curative action. Treatment with the serum of normal rabbits may prolong the course of pneumococcus infection… (More)
It has been possible by rapid transfers alone, not only to maintain the virulence for mice of the pneumococcus in artificial media but also to restore a certain degree of virulence to cultures previously rendered non-virulent by less rapid transfers in the same medium. For these results the presence of enriching fluids such as blood or serum is not… (More)
Antigens were prepared from the culture filtrates of tubercle bacilli and by extraction of washed and dried organisms with organic and aqueous solvents and from tissues of organs showing tuberculous lesions. A comparison of these preparations by means of the complement fixation test showed that the aqueous extracts were most active antigenically. The… (More)
Preventive medicine deserves a wider field than merely communicable disease. Some developments, like prevention of diseases of middle life are successful, others like health insurance have been less so. This has been hardly more than a sick-benefit movement. Industrial medicine is most valuable from the financial point of view as well as that of health.
Horses immunized to Type I pneumococci developed serum, 0.1 cc. of which protected against 0.5 cc. of a virulent culture, 0.000001 cc. of which killed mice in less than 40 hours. Protective tests of serum from horses immunized to Type II organisms varied, 0.1 cc. protecting, however, in certain instances against 0.1 and 0.01 cc. of virulent homologous… (More)