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  • Augustine Chen, Henry Beetham, +7 authors Parry J Guilford
  • Biology, Medicine
  • BMC Cancer
  • 2014 (First Publication: 30 July 2014)
  • BackgroundE-cadherin is an adherens junction protein that forms homophilic intercellular contacts in epithelial cells while also interacting with the intracellular cytoskeletal networks. It has rolesExpand
  • Bryony J. Telford, Augustine Chen, +7 authors Parry J Guilford
  • Biology, Medicine
  • Molecular Cancer Therapeutics
  • 2015 (First Publication: 16 March 2015)
  • The CDH1 gene, which encodes the cell-to-cell adhesion protein E-cadherin, is frequently mutated in lobular breast cancer (LBC) and diffuse gastric cancer (DGC). However, because E-cadherin is aExpand
  • Andrew Single, Henry Beetham, Bryony J. Telford, Parry J Guilford, Augustine Chen
  • Biology, Medicine
  • Journal of biomolecular screening
  • 2015 (First Publication: 17 September 2015)
  • Cell viability assays fulfill a central role in drug discovery studies. It is therefore important to understand the advantages and disadvantages of the wide variety of available assay methodologies.Expand