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Several epidemiological studies have indicated that residential or occupational exposure to 50 or 60 Hz magnetic fields (MF) may increase the risk of breast cancer, possibly by suppression of pineal production of the oncostatic hormone melatonin. In view of the methodological problems of epidemiological studies on MF exposure and cancer risk, laboratory(More)
Although Lewis rats are frequently used in biomedical research, little is known about their life-data and spontaneous pathology. Therefore, it was the aim of this study to determine the life expectancy, spectrum and incidence of spontaneous neoplasms of the inbred rat strain LEW/Han. A total of 629 LEW/Han rats (305 females and 324 males) from a specified(More)
An improved method for pinealectomizing rats and other small laboratory rodents is described which avoids bleeding and allows excision of the organ under exact visual control. After removing a small piece of the skull dorsal to the confluence of the transverse and dorsal sagittal sinuses, the latter is ligated and cut. The underlying pineal gland is then(More)
OBJECTIVE The objective of this study was to determine whether prophylactic treatment with oral broad-spectrum antimicrobial therapy improves pregnancy outcomes in twin gestations. METHODS Patients with twin gestations between 24 and 32 weeks were randomized to receive amoxicillin/clavulanic acid or placebo. Those patients randomized before 24 weeks(More)
Extravasation of contrast medium following retrograde pyelography may occur when excessive pressure is used during injection of the contrast medium, direct trauma during manipulation of the ureteral catheter or pre-existing ureteral disease. Extravasation of contrast medium occurring in a ureteral tumour is rare. A case where extravasation of contrast(More)
Syrian golden hamsters were treated with N-nitrosobis-(2-oxopropyl)amine (BOP) and/or diethylstilbestrol (DES) for lifetime. After BOP treatment the hamsters developed high incidences of pancreatic neoplasms, but DES failed to show any effect on these or other tumours.
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