Audello Rivera

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We have previously reported increased activity of Na+/H+ and Na+/Li+ exchanges in red blood cells (RBC) of patients with hypertension and diabetic nephropathy. The presence in human red blood cells (RBC) of insulin receptors has led us to examine the effects of this hormone on the kinetic parameters of Na+/H+ exchange as a first approach to define its(More)
Abnormalities of intracellular calcium homeostasis and sodium-proton exchange have been implicated in the pathophysiology of essential hypertension. To further define the nature of cytosolic calcium abnormalities and whether they relate to increased sodium-proton exchange in hypertension, we have studied peripheral lymphocytes from normotensive and(More)
We have previously described significant differences in plasma amino acids, bile flow and biliary bile acid output between animals infused either glucose or glucose+amino acids. The present study was undertaken to determine liver, bile and brain amino acid responses to the infusion of these various nutrients. Adult male Sprague-Dawley rats (225-325g) were(More)
Tryptophan (T) photooxidized in the presence of riboflavin (R) alters hepatic function in developing animals. Solutions of T (48 um/ml) were either exposed to (+L) or protected from (-L) light for 12 hours (in the presence, +R, or absence, -R, of 1 mg/ dl of R). Two-week old suckling gerbils were randomly assigned to daily intraperitoneal injections of(More)
Increased red blood cell sodium-lithium countertransport (SLC) activity and elevated intracellular calcium have been observed in hypertensive patients. The association of these ion transport abnormalities with each other and with another phenotype, insulin resistance, has been suggested. We investigated whether elevated SLC activity and increased lymphocyte(More)
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