Aude Ambresin

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PURPOSE To study the efficacy and safety of deep sclerectomy with collagen implant in one eye versus trabeculectomy in the other eye of the same patient. METHODS The authors conducted a nonrandomized prospective trial of 20 patients with medically uncontrolled primary and secondary open-angle glaucoma. Patients with bilateral medically uncontrolled(More)
Retinal angiomatous proliferation (RAP) is a distinct variant of neovascular age-related macular degeneration (AMD). The aim of this study is to evaluate the functional and anatomic outcome after intravitreal ranibizumab (Lucentis) treatment in patients with RAP. Prospective study of consecutive patients with newly diagnosed or recurrent RAP treated with(More)
Cone-rod dystrophies are inherited dystrophies of the retina characterized by the accumulation of deposits mainly localized to the cone-rich macular region of the eye. Dystrophy can be limited to the retina or be part of a syndrome. Unlike nonsyndromic cone-rod dystrophies, syndromic cone-rod dystrophies are genetically heterogeneous with mutations in genes(More)
PURPOSE To determine the epidemiology of Behçet's disease in Western Switzerland and to study the characteristics of ocular disease. METHODS Patients newly diagnosed with Behçet's disease, seen from January 1990 to December 1998 at Hôpital Jules Gonin, La Source Eye Center, and the Division of Immunology and Allergy, University of Lausanne, were analyzed.(More)
BACKGROUND/AIMS Complement factor H (CFH) Y402H polymorphism shows a strong association with age-related macular degeneration (AMD). Although the phenotypic concordance of AMD has been shown in sibling/twin studies, little is known about the genotype-phenotype association. In this study, we investigated whether CFH Y402H is associated with early phenotypic(More)
PURPOSE We evaluate the functional and anatomic outcome after intravitreal ranibizumab treatment in patients with choroidal neovascularization (CNV) related to chronic central serous chorioretinopathy (CSC). METHODS This is a small case series of 5 eyes with CNV associated with chronic CSC treated with intravitreal injection of 0.5 mg ranibizumab in the(More)
PURPOSE To study the effect of various baseline factors, particularly the type of drug (ranibizumab vs aflibercept), on the functional and anatomic response of treatment-naïve pigment epithelial detachment (PED) associated with neovascular age-related macular degeneration (neovascular AMD), after 3 intravitreal injections. DESIGN Retrospective consecutive(More)
PURPOSE To determine the effectiveness of vitrectomy, internal tamponade, and peripheral 360 degrees retinal photocoagulation in the management of giant retinal tears (GRTs). PARTICIPANTS Eighteen eyes of 18 consecutive patients with GRTs were operated on at Jules Gonin Eye Hospital between 1992 and 1999. None of them had previous vitreoretinal surgery.(More)
PURPOSE To describe microvascular abnormalities and capillary density in macular telangiectasia type 1 (MT1) using optical coherence tomography angiography (OCTA), and correlate them with fluorescein angiography (FA). DESIGN Observational case series. METHODS Seven patients with MT1 and 12 age-matched controls were included. Focal microvascular(More)
PURPOSE The purpose of this study was to report the 2-year outcome of an individually tailored 'observe-and-plan' treatment regimen for neovascular age-related macular degeneration (nAMD), and to investigate its clinical value in terms of functional outcome. This regimen aimed to reduce the clinical burden (visits) by employing individually fixed injection(More)