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Fiber dissection techniques were used to study the limbic system, in particular the Papez circuit. The course, length and anatomical relations of the structures that make up the Papez circuit were delineated. Ten previously frozen and formalin-fixed cadaveric human brains were used, and dissected according to the fiber dissection techniques of Klingler et(More)
OBJECTIVE Using a fiber-dissection technique, our aim is to study the fiber bundles of the optic radiation. We focused on the course, the length, anatomical relations with lateral ventricle and the relevance of these finding during surgery in the region. MATERIALS AND METHODS Five previously frozen and formalin-fixed cadaveric human brains were used. The(More)
MicroRNAs (miRNAs) are short non-coding RNAs that interfere with translation of specific target mRNAs and thereby regulate diverse biological processes. Recent studies have suggested that miRNAs might have a role in osteoblast differentiation and bone formation. Here, we show that miR-542-3p, a well-characterized tumor suppressor whose downregulation is(More)
OBJECTIVE We review our experience with the use of the plate and screw method of fixation in the treatment of 160 patients with atlantoaxial instability during a 14-year period at our center. We previously described this method of fixation in 1994. METHODS Between 1988 and 2001, 160 patients with atlantoaxial instability were treated with the use of a(More)
BACKGROUND Medulloblastoma has recently been found to consist of 4 molecularly and clinically distinct subgroups: WNT, Sonce hedgehog (SHH), Group 3, and Group 4. Deregulated microRNA expression is known to contribute to pathogenesis and has been shown to have diagnostic and prognostic potential in the classification of various cancers. METHODS Molecular(More)
Row-Diagonal Parity (RDP) is a new algorithm for protecting against double disk failures. It stores all data unencoded, and uses only exclusive-or operations to compute parity. RDP is provably optimal in computational complexity, both during construction and reconstruction. Like other algorithms, it is optimal in the amount of redundant information stored(More)
OBJECTIVE The surgical strategies and outcomes for 70 patients operated on for tuberculum sellae meningioma were analyzed retrospectively. The analysis was based on factors that probably determined the difficulties encountered during surgery, assisted in predicting the extent of resectability, and helped in predicting the surgical outcome. METHODS Seventy(More)
OBJECT The author discusses the successful preliminary experience of treating selected cases of basilar invagination by performing atlantoaxial joint distraction, reduction of the basilar invagination, and direct lateral mass atlantoaxial plate/screw fixation. METHODS Twenty-two patients with basilar invagination-in which the odontoid process invaginated(More)
OBJECT This study is a retrospective analysis of 60 surgically treated patients with 64 peripheral nerve sheath tumors (PNSTs) at the second cervical (C-2) nerve root. The anatomical subtleties of these tumors and their implications for surgical strategy when compared with other spinal PNSTs and other tumors in the foramen magnum region are reviewed. (More)