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In this paper, we introduce and study an efficient regular queries processing algorithm on a very large XML data set which is fragmented and stored on different machines. The machines are connected by the high speed interconnection. In this system the efficiency of a query processing algorithm depends on two main factors: the waiting time for the answer and(More)
The most aggressive and rare manifestation of multiple myeloma is plasma cell leukaemia (PCL). While secondary form of PCL represents those heavily pretreated cases when leukaemic transformation develops terminally after intensive chemotherapy in patients with multiple myeloma, primary cases are characterized by leukaemic symptoms present at diagnosis. The(More)
RDF is a flexible data representation model. Due to its flexibility and simplicity it has become a popular framework, hence the amount of RDF data is increasing fast. Querying massive amount of data is a serious challenge in general and it is true for RDF data as well. In this paper we investigating how to evaluate SPARQL queries on a distributed system. We(More)
The aim of this study was to see whether pleiotropic or myeloid hematopoietic growth factors, which do not stimulate normal lymphoid cells, can induce proliferation of blast cells of the acute lymphoid leukemia (ALL) of childhood. Bone marrow cells of 13 children with untreated ALL (nine common ALL, two myeloid antigen positive ALL and two early T-cell ALL)(More)
Our preliminary data indicate that rosiglitazone may be myeloprotective. We investigated whether it can modify bone marrow recovery. Five-day pre-treatment with rosiglitazone significantly accelerated recovery of 5-fluorouracil-damaged bone marrow in mice. Frequency and femoral content of granulocyte-macrophage progenitors reached mean baseline faster in(More)
INTRODUCTION Fludarabine is the most commonly used purine analog, its mechanism of action is complex. Fludarabine inhibits DNA synthesis, acts on non-dividing (G0 phase) cells influencing apoptosis. PATIENTS, RESULTS, CONCLUSIONS In our institute 47 patients were treated with fludarabine or fludarabine based combination chemotherapy. Fludarabine was given(More)
Dendritic cell-based active immunotherapies of cancer patients are aimed to provoke the proliferation and differentiation of tumor-specific CD4+ and CD8+ T-lymphocytes towards protective effector cells. Isolation and in vitro differentiation of circulating blood monocytes has been established a reasonable platform for adoptively transferred DC-based(More)
The association of coagulation factors with leukocytes have been demonstrated in several previous studies. This study was designed to study the sensitivity and specificity of factor XIII subunit A (FXIII-A) labelling in cultured myeloblastic and monoblastic cell lines and to investigate the intracytoplasmic expression of FXIII-A in de novo acute myeloid(More)
Clustering is an important tool to explore the hidden structure of large databases. There are several algorithms based on different approaches (hierarchical, partitional, density-based, model-based, etc.). Most of these algorithms have some discrepancies, e.g. they are not able to detect clusters with convex shapes, the number of the clusters should be a(More)