Atsushi Okamoto

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Micronucleation, mediated by interphase nuclear budding, has been repeatedly suggested, but the process is still enigmatic. In the present study, we confirmed the previous observation that there are lamin B1-negative micronuclei in addition to the positive ones. A large cytoplasmic bleb was found to frequently entrap lamin B1-negative micronuclei, which(More)
The presence of micronuclei in mammalian cells is related to several mutagenetic stresses. In order to understand how micronuclei emerge, behave in cells, and affect cell fate, we performed extensive time-lapse microscopy of HeLa H2B-GFP cells in the presence of hydroxyurea at low concentration. Micronuclei formed after mitosis from lagging chromatids or(More)
Satellite line scanner imagery such as that of SPOT and MOMS-02 is usually analysed via a collinearity equation approach based on projective transformation. This paper discusses the application of an alternative approach to the triangulation of satellite line scanner imagery, namely affine projection. The approach involves an initial transformation of the(More)
Adenosine A2b receptor (ADORA2B) encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. Little is known about the relevance of ADORA2B to human malignancy including oral squamous cell carcinoma (OSCC). We aimed to(More)
We propose a mode multiplexer based on volume holograms to realize a simple and efficient mode-division-multiplexed transmission system that supports a large number of modes. Selective multiexcitation of three spatial modes into a conventional multimode fiber is experimentally demonstrated. This device could potentially multiplex 10 or more modes. Future(More)
Angiopoietin-like 3 (ANGPTL3), which is involved in new blood vessel growth and stimulation of mitogen-activated protein kinase (MAPK), is expressed aberrantly in several types of human cancers. However, little is known about the relevance of ANGPTL3 in the behavior of oral squamous cell carcinoma (OSCC). In this study, we evaluated ANGPTL3 mRNA and protein(More)
This study proposes a volume holographic demultiplexer (VHDM) for extracting the spatial modes excited in a multimode fiber. A unique feature of the demultiplexer is that it can separate a number of multiplexed modes output from a fiber in different directions by using multi-recorded holograms without beam splitters, which results in a simple configuration(More)
— A fully integrated voltage multiplier with low startup voltage (V START) and fast startup is developed for the energy harvesting (e.g. thermoelectric energy harvester). The generation of the high frequency clock signal with large amplitude without using off-chip components is a key to achieve the voltage multiplier. The proposed passive clock boost using(More)
This study proposes holographic diversity interferometry (HDI), a system that combines information from spatially dispersed plural image sensors to reconstruct complex amplitude distributions of light signals. HDI can be used to generate four holographic interference fringes having different phases, thus enabling optical phase detection in a single(More)