Atsushi Okamoto

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Micronucleation, mediated by interphase nuclear budding, has been repeatedly suggested, but the process is still enigmatic. In the present study, we confirmed the previous observation that there are lamin B1-negative micronuclei in addition to the positive ones. A large cytoplasmic bleb was found to frequently entrap lamin B1-negative micronuclei, which(More)
The presence of micronuclei in mammalian cells is related to several mutagenetic stresses. In order to understand how micronuclei emerge, behave in cells, and affect cell fate, we performed extensive time-lapse microscopy of HeLa H2B-GFP cells in the presence of hydroxyurea at low concentration. Micronuclei formed after mitosis from lagging chromatids or(More)
Satellite line scanner imagery such as that of SPOT and MOMS-02 is usually analysed via a collinearity equation approach based on projective transformation. This paper discusses the application of an alternative approach to the triangulation of satellite line scanner imagery, namely affine projection. The approach involves an initial transformation of the(More)
Adenosine A2b receptor (ADORA2B) encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. Little is known about the relevance of ADORA2B to human malignancy including oral squamous cell carcinoma (OSCC). We aimed to(More)
Angiopoietin-like 3 (ANGPTL3), which is involved in new blood vessel growth and stimulation of mitogen-activated protein kinase (MAPK), is expressed aberrantly in several types of human cancers. However, little is known about the relevance of ANGPTL3 in the behavior of oral squamous cell carcinoma (OSCC). In this study, we evaluated ANGPTL3 mRNA and protein(More)
— A fully integrated voltage multiplier with low startup voltage (V START) and fast startup is developed for the energy harvesting (e.g. thermoelectric energy harvester). The generation of the high frequency clock signal with large amplitude without using off-chip components is a key to achieve the voltage multiplier. The proposed passive clock boost using(More)
Recently, scene recognition is becoming an additional function in digital camera. Automatic scene understanding is a highest-level operation in computer vision, and it is a very difficult and largely unsolved problem. The conventional methods usually use global features (such as color histogram, texture, edge) for image representation and recognize scene(More)
Earth is the only terrestrial planet in our solar system where an oceanic plate subducts beneath an overriding plate. Although the initiation of plate subduction requires extremely weak boundaries between strong plates, the way in which oceanic mantle rheologically weakens remains unknown. Here we show that shear-enhanced hydration reactions contribute to(More)
It is essential to extract nonlinear dynamics from time-series data as an inverse problem in natural sciences. We propose a Bayesian statistical framework for extracting nonlinear dynamics of surface heterogeneous reactions from sparse and noisy observable data. Surface heterogeneous reactions are chemical reactions with conjugation of multiple phases, and(More)