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OBJECTIVES To compare disease activity and the improvement of disease activity evaluated between by Disease Activity Score 28 using erythrocyte sedimentation rate (DAS28-ESR) and by DAS28 using C-reactive protein (DAS28-CRP) in Japanese patients with rheumatoid arthritis (RA). METHODS Data from 3073 RA patients registered in the large cohort database(More)
The tree partition number of an r-edge-colored graph G, denoted by t r (G), is the minimum number k such that whenever the edges of G are colored with r colors, the vertices of G can be covered by at most k vertex-disjoint monochromatic trees. We determine t 2 (K(n 1 , n 2 ,. .. , n k)) of the complete k-partite graph K(n 1 , n 2 ,. .. , n k). In(More)
BACKGROUND AND AIMS Adrenomedullin (ADM) is a member of the calcitonin family of regulatory peptides, and is reported to have anti-inflammatory effects in animal models of Crohn's disease (CD). We investigated the therapeutic effects of daikenchuto (DKT), an extracted Japanese herbal medicine, on the regulation of endogenous ADM in the gastrointestinal(More)
OBJECTIVE To evaluate perioperative changes in rheumatoid arthritis (RA) patients treated with tocilizumab. METHODS We collected RA cases with tocilizumab and orthopaedic surgery from 1999 to 2010. Incidences of postoperative infections, delayed wound healing, and RA symptom flare-ups were extracted from the data for comparison with patients without these(More)