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Endocrine therapy is the standard treatment for advanced prostate cancer; however, relapse occurs in most patients with few treatment options available after recurrence. To overcome this therapeutic… Continue Reading
Abstract Crack deflection is a potential mechanism for toughening essentially brittle materials. Deflection generally occurs along grain boundaries and is enhanced by particles with high aspect… Continue Reading
The difference in bioavailability of nicorandil, a newly developed antianginal agent, before and after eating was studied in 10 healthy male volunteers. The phar macokinetic parameters after single… Continue Reading
In the subway lines of Tokyo Metro, there are many tight curves that may cause squeal noise, excessive rail/wheel wear and also rail corrugation. To solve these serious problems, an onboard friction… Continue Reading
Abstract A 1,2-disubstituted ferrocene derivative, 2-[(dimethylamino)methyl]-1-hydroxyferrocene (I), was prepared from 2-[(dimethylamino)methyl]-1-iodoferrocene via… Continue Reading