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Valproic acid and ASK1 deficiency ameliorate optic neuritis and neurodegeneration in an animal model of multiple sclerosis

• Yuriko Azuchi, Atsuko Kimura, +6 authors Takayuki Harada
• Neuroscience Letters
• 2017

Optic neuritis, which is an acute inflammatory demyelinating syndrome of the central nervous system, is one of the major complications in multiple sclerosis (MS). Herein, we investigated the… (More)

Application of molecular orbital calculations to interpret the chlorophyll spectral forms in pea photosystem II.

• Atsuko Nishigaki, Shigeru Ohshima, Koji Nakayama, Masuo Okada, Umpei Nagashima
• Photochemistry and photobiology
• 2001

The energy and oscillator strength of electronic transitions of chlorophyll (Chl)-amino acid complexes were calculated by using molecular orbital methods. The energies varied widely with coordinated… (More)

Destruxin E decreases Beta-amyloid generation by reducing colocalization of beta-amyloid-cleaving enzyme 1 and beta-amyloid protein precursor.

• Naohiro Itoh, Masayasu Okochi, +25 authors Masatoshi Takeda
• Neuro-degenerative diseases
• 2009

Alzheimer-disease-associated beta-amyloid (Abeta) is produced by sequential endoproteolysis of beta-amyloid protein precursor (betaAPP): the extracellular portion is shed by cleavage in the… (More)

Further evidence concerning catecholamine metabolism in polycystic ovary syndrome following Gn-RH administration.

• Kiyoshi Yoshino, Kentaro Takahashi, Atsuko Nishigaki, Yoshiki Eda, Manabu Kitao
• International journal of fertility
• 1992

The role of catecholamine activity in the GnRH-LH system among cases of polycystic ovary syndrome was investigated by high-performance liquid chromatography using an electrochemical detector. We… (More)

On the relationship between endocrine and ovulatory abnormalities, and polycystic ovaries as diagnosed by ultrasonography.

• Kentaro Takahashi, Kiyoshi Yoshino, Atsuko Nishigaki, Yoshiki Eda, Manabu Kitao
• International journal of fertility
• 1992

The present study was undertaken to investigate the relationship between serum testosterone levels, the menstrual cycle, and polycystic ovaries as shown by ultrasonographic methods. The patients were… (More)

[The relations between doses of streptozotocin and pathosis in induced diabetes mellitus].

• Atsuko Nishigaki, Hiroyasu Noma, Takashi Kakizawa
• Shika gakuho. Dental science reports
• 1989

Tail-vein injections of streptozotocin (STZ) in various doses (20-60 mg/kg body weight) were used to induce diabetes mellitus in male rats of the Sprague-Dawley strain. Resulting pathosis was… (More)

Ultrasonographic evaluation of adrenal involution during antenatal and neonatal periods.

• Kohkichi Hata, Hiroshi Nagata, +4 authors Manabu Kitao
• Gynecologic and obstetric investigation
• 1988

Using real-time ultrasonography, 25 adrenal glands from prenatal to neonatal periods were prospectively examined to assess the process of shrinkage. A similar sonographic structure was seen in both… (More)

Plasma catecholamine metabolites and polycystic ovary syndrome.

• Kiyoshi Yoshino, Kentaro Takahashi, Atsuko Nishigaki, Yoshiki Eda, Manabu Kitao
• Asia-Oceania journal of obstetrics and…
• 1990

It has been postulated that catecholamine metabolism may be altered in cases of polycystic ovary syndrome. To search for possible correlations between catecholamine metabolism and hormonal… (More)

Characterization of three forms of light-harvesting chlorophyll a/b-protein complexes of photosystem II isolated from the green alga, Dunaliella salina.

• Atsuko Nishigaki, Shigeru Ohshima, Koji Nakayama
• Plant & cell physiology
• 2000

Three forms of light-harvesting chlorophyll a/b-protein complexes of photosystem II (LHC II) were isolated from the thylakoid membranes of Dunaliella salina grown under different irradiance… (More)

Peripheral catecholamine metabolites and free testosterone in patients with polycystic ovary syndrome.

• Kiyoshi Yoshino, Kentaro Takahashi, Yoshiki Eda, Atsuko Nishigaki, Manabu Kitao
• Nihon Sanka Fujinka Gakkai zasshi
• 1991

Polycystic ovary syndrome (PCOS) is characterized by chronic anovulation, elevated serum estrogen and androgen levels, and inappropriate gonadotropin secretion. The present study compares the… (More)

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