Atsuko Negishi

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Adeno-associated virus (AAV) has been widely used as a viral vector to deliver genes to animal and human tissues in gene therapy studies. Both AAV-2 and AAV-3 use cell surface heparan sulfate (HS), a highly sulfated polysaccharide, as a receptor to establish infections. In this study, we used atomic force microscopy (AFM) to investigate the interaction of(More)
  • M Gail Jones, Alexandra Bokinsky, Tom Tretter, Atsuko Negishi, Dennis Kubasko, Russell Taylor +1 other
  • 2004
Advances in microscopy are not only allowing scientists to investigate phenomena at ever-decreasing scale, but also permitting sensory data beyond the visual to be gathered. This chapter describes research on middle and high school students' use of remote microscopy with a new scientific tool called the nanoManipulator, which enabled them to reach out and(More)
The impact of haptic feedback on the perception of unknown objects (10 without texture, 10 with texture, and 2 complex shapes) was examined. Using a point probe (a PHANTOM), three treatment groups of students (visual, haptic, and visual plus haptic feedback) explored a set of virtual objects. The visual treatment group observed the objects through a small(More)
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