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This paper presents the results of an exploratory study that examined a possible connection between investments in Information Technology and changes in the market value of companies in Japan. The event-study methodology, which focuses on the change of stock price as a result of announcements about Information Technology investments, was applied. The main(More)
Periodontitis is an inflammatory disease causing loss of tooth-supporting periodontal tissue. Disease susceptibility to the rapidly progressive form of periodontitis, aggressive periodontitis (AgP), appears to be influenced by genetic risk factors. To identify these in a Japanese population, we performed whole exome sequencing of 41 unrelated generalized or(More)
BACKGROUND Variability in intracoronary computed tomography (CT) number may influence vessel quantification. We confirmed the feasibility of a novel method for measuring vessel diameter and area using coronary CT angiography (CCTA) with an optimized intracoronary CT number, 350 HU. METHODS We performed intravascular ultrasound (IVUS) imaging in 52(More)
A major challenge in current exome sequencing in autosomal recessive (AR) families is the lack of an effective method to prioritize single-nucleotide variants (SNVs). AR families are generally too small for linkage analysis, and length of homozygous regions is unreliable for identification of causative variants. Various common filtering steps usually result(More)
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