Atla Bhagyalakshmi

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There is evidence suggesting that fluid shear stress activates phospholipid turnover in endothelial cells, but it is not clear which phospholipids are involved in the transduction of the flow signal. Cultured human umbilical-vein endothelial cells were prelabeled with [14C]-arachidonic acid and subjected to laminar shear stresses of 0.4, 1.4 and 22 dyn/cm2(More)
Human umbilical vein endothelial cells at confluence were subjected to steady shear flow. It was previously shown that flow induced a burst in prostacyclin production followed by a sustained stimulation of production several fold higher than basal levels (1). In the presence of EGTA, prostacyclin production was inhibited in the steady state phase by 74%.(More)
Changes in oxidative metabolism were studied in hepatopancreas, muscle, and hemolymph of the edible crab Scylla serrata, exposed to a sublethal concentration (2.5 ppm) of cadmium chloride. A significant decrease in glycogen, total carbohydrates, and pyruvate and an increase in lactate levels in hepatopancreas and muscle were observed. Hemolymph sugar levels(More)
Crabs, Oziotelphusa senex senex, were exposed to sublethal concentration (0.2 ppm) of fenvalerate, and changes in the protein metabolism of hepatopancreas and muscle were investigated. The levels of total and soluble proteins were decreased, whereas the levels of the free amino acids and activity levels of protease, alanine transaminase, aspartate(More)
Chronic sumithion toxicity in experimental crabs was induced by exposing them for 15 and 30 days to 0.04 ppm sumithion solution. The enzymes concerned with glycogenolytic metabolism (phosphorylase), glycolytic metabolism (aldolase), aerobic metabolism [succinate dehydrogenase (SDH), malate dehydrogenase (MDH)], anaerobic metabolism, lactate dehydrogenase(More)
Healthy crabs (Oziotelphusa senex senex) were exposed to 3 concentrations of sumithion, with a control group over a 30-day period. The glycogen content of the hepatopancreas was depleted on acute exposure but was elevated after acclimatization. The glycogen phosphorylase activity was elevated on acute exposure, whereas phosphorylase activity decreased after(More)
Indian rice field crabs, exposed to a lethal concentration (LC50/24 h = 39 mg/l) of benzene hexachloride (BHC) to study acute toxic effects, showed changes in hemolymph glucose and protein. The effect of BHC resulted in hyperglycemia and hyperproteinemia.
Muscle nitrogen metabolism was studied in the crab, Oziotelphusa senex senex Fabricius, following acute (1 day) and chronic (20 days) exposure to 0.1 ppm sumithion solution. Proteolysis in the muscle tissue in acute exposure was increased after exposure for 24 h. The muscle tissue of chronically exposed crabs seemed to develop a more efficient mechanism for(More)
OBJECTIVES To compare the levels of pentraxin 3 (PTX-3) in gingival crevicular fluid (GCF) in patients undergoing orthodontic canine retraction with active tieback and nickel titanium (NiTi) coil spring. MATERIALS AND METHODS Fifteen patients of the age group 15-25 years with first premolar extraction undergoing canine retraction were selected. One month(More)