Athina Mylona

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The first site exhibiting hematopoietic activity in mammalian development is the yolk-sac blood island, which originates from the hemangioblast. Here we performed differentiation assays, as well as genome-wide molecular and functional studies in blast colony-forming cells to gain insight into the function of the essential Ldb1 factor in early primitive(More)
G Kong, Y-I Chang, X You, EA Ranheim, Y Zhou, CE Burd and J Zhang McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, USA; Institute of Physiology, National Yang-Ming University, Taipei City, Taiwan; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, University of(More)
Cardiac stem/progenitor cells hold great potential for regenerative therapies; however, the mechanisms regulating their expansion and differentiation remain insufficiently defined. Here we show that Ldb1 is a central regulator of genome organization in cardiac progenitor cells, which is crucial for cardiac lineage differentiation and heart development. We(More)
The first site exhibiting hematopoietic activity in mammalian development is the yolk sac blood island, which originates from the hemangioblast. Here we performed differentiation assays, as well as genome-wide molecular and functional studies in BL-CFCs to gain insight into the function of the essential Ldb1 factor in early primitive hematopoietic(More)
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