Denosumab and zoledronic acid are potent antiresorptives. In this study in patients pre-treated with zoledronic acid, denosumab achieved similar increases with zoledronic acid in lumbar spine BMD… (More)
Although vaspin is regarded an insulin-sensitizing adipokine, its role in gestational diabetes mellitus (GDM) is currently unknown. We aimed to evaluate serum vaspin levels and their correlation with… (More)
In vitro data suggest that myokine irisin may affect bone metabolism by promoting osteoblast differentiation while inhibiting osteoclast differentiation. In this study, circulating irisin levels were… (More)
CONTEXT
Decreased bone formation due to a coupling effect limits bone mass increases after antiresorptive treatment.
OBJECTIVE
The purpose of this study was to compare the effects of 2 potent… (More)
The gastrointestinal tract has a major role in digestion and absorption of nutrients while playing a leading role in defense of the body. It forms a shield against the invasion of various… (More)
Periostin is a secreted extracellular matrix protein preferentially expressed in bone by osteocytes and periosteal osteoblasts. Reduced periostin expression may affect osteoblast differentiation and… (More)
BACKGROUND
Struma ovarii is a rare cause of hyperthyroidism, while coexistence with Graves' disease has been scarcely reported.
PATIENT FINDINGS
We report a patient with Graves' disease and… (More)
An acute phase response (APR) is frequently observed in patients treated with intravenous (i.v.) zoledronate (ZOL). We aimed to define clinical and laboratory parameters that may predict ZOL-induced… (More)
INTRODUCTION
The aim of the present study was to investigate whether normal pregnancy represents a complex state of oxidative stress, inflammation and insulin resistance.
SUBJECTS AND METHODS
One… (More)
OBJECTIVE
The evaluation of circulating semaphorin-4D (sema4D) and plexin-B1 in postmenopausal women with low bone mass and the effect of antiresorptive or osteoanabolic treatment.
METHODS
Serum… (More)