Athanassias Konstantinidis

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In sensitized individuals, exposure to allergens such as Dermatophagoides pteronyssinus (Der p) causes Th2 polarization and release of cytokines, including IL-4 and IL-13. Because Der p extracts also have direct effects on epithelial cells, we hypothesized that allergen augments the effects of Th2 cytokines by promoting mediator release from the bronchial(More)
The host immune response plays a key role in bacteria-induced alveolar bone resorption. Endogenous control of the magnitude and duration of inflammatory signaling is considered an important determinant of the extent of periodontal pathology. Suppressor of cytokine signaling (SOCS) proteins are inhibitors of cytokine signaling pathways and may play a role in(More)
Cell cultures of L929 and BHK21/C13 cells were used to evaluate the toxicity of a newly introduced bleaching agent (Colgate Platinum) compared to hydrogen peroxide, an established bleaching agent. The cell reaction was determined by a quantitative technique at 24 h and 72 h. Both bleaching materials had a dose-dependent effect on cell viability.(More)
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