Atena Zahedi

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There is a foundational need for quality control tools in stem cell laboratories engaged in basic research, regenerative therapies, and toxicological studies. These tools require automated methods for evaluating cell processes and quality during in vitro passaging, expansion, maintenance, and differentiation. In this paper, an unbiased, automated(More)
Actin-regulating proteins, such as cofilin, are essential in regulating the shape of dendritic spines, and synaptic plasticity in both neuronal functionality as well as in neurodegeneration related to aging. The analysis of the motility of cofilin in fluorescence video-microscopy allows the discovery of its effects on cell functions. However, the flow of(More)
Cofilin and other Actin-regulating proteins are essential in regulating the shape of dendritic spines, which are sites of neuronal communications in the brain, and their malfunctions are implicated in neurodegeneration related to aging. The analysis of cofilin motility in dendritic spines using fluorescence video-microscopy may allow for the discovery of(More)
Thirdhand cigarette smoke (THS) was recently recognized as an environmental health hazard; however, little is known about it effects on cells. Mitochondria are sensitive monitors of cell health and report on environmentally induced stress. We tested the effects of low levels of THS extracted from terry cloth on mitochondrial morphology and function using(More)
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