Atchasai Siritantikorn

Learn More
Rat liver microsomal glutathione transferase 1 (MGST1) is a membrane-bound enzyme that displays both glutathione transferase and glutathione peroxidase activities. We hypothesized that physiologically relevant levels of MGST1 is able to protect cells from oxidative damage by lowering intracellular hydroperoxide levels. Such a role of MGST1 was studied in(More)
Nondeletional gene mutations giving rise to alpha-thalassemia can be found at polymorphic frequency in Southeast Asia. Although the most common is hemoglobin Constant Spring (Hb CS), caused by a termination codon mutation (UAA --> CAA, Gln) in the alpha2-globin gene and resulting in reduced synthesis of the elongated alpha-globin variant, Hb Pakse (UAA -->(More)
Glutathione transferases (GSTs) are often upregulated in tumors and have been suggested to play an important role in multiple drug resistance in cancer chemotherapy. As a consequence GST-dependent pro-drugs and inhibitors are being developed. Little is known, however, on the potential role of membrane-bound GSTs in drug resistance despite the fact that(More)
OBJECTIVES We evaluated the effects of lifestyle modification (LM) on lipid profile, oxidative stress and serum-stimulated human coronary artery endothelial cell (HCAEC) viability in coronary artery disease (CAD) patients after 6months. DESIGN AND METHODS Thirty patients with CAD were randomly assigned to LM intervention (n=15) and usual care control(More)
A comparative study between the classical Westergren and the new sealed vacuum extraction methods for erythrocyte sedimentation rate determination was performed on 80 individual subjects. The comparison-of-methods plot sealed vacuum extraction method (X) vs Westergren method (Y) gave a least square linear regression equation of Y = 1.001 X + 0.03 (r = 0.99)(More)
A comparative study between standard Westergren and erythrocyte sedimentation pipette (Sediplast) methods for determination of erythrocyte sedimentation rate was performed on 80 individual subjects. From the study, the comparison-of-methods plot Sediplast method (X) vs Westergren method (Y) gave the least square linear regression equation of Y = 1.001 X -(More)
BACKGROUND Presently, the counting of leukocytes in cerebrospinal fluid (CSF) is still performed manually. This requires sufficiently experienced medical technologists. At present, specific automated systems for CSF cell counting are not available. In this study, we evaluated the use of the automated hematology analyzer, Technicon H*3 in the analysis of(More)
To compare between standard Westergren and modified microhaematocrit method for determination for erythrocyte sedimentation rate Study design: A laboratory method comparative study. Subjects: blood samples from 80 individual subjects. For each subject, two methods for erythrocyte sedimentation rate determination were performed. The first method was the(More)
  • 1