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While current pharmacotherapies are efficacious, there remain a clear shortfall between symptom remission and functional recovery. With the explosion in our understanding of the biology of these disorders, the time is ripe for the investigation of novel therapies. Recently depression is conceptualized as an immune-inflammatory and nitro-oxidative stress(More)
rationale-the efficacy of minocycline as an adjunctive treatment for major depressive disorder: a double blind, randomised, placebo controlled trial, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. While current pharmacotherapies are efficacious, there remain a clear(More)
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