• Publications
  • Influence
New β-Caryophyllene-Derived Terpenoids from the Soft Coral Sinularia nanolobata
TLDR
The cytotoxicity of 1−6 against the growth of a limited panel of cancer cell lines is described and the structures of 1+5 were elucidated on the basis of extensive spectroscopic analyses and by comparison of the spectral data with those of the related metabolites.
A novel antioxidant phenanthrenoid dimer from Juncus acutus L.
TLDR
It was found that dimerisation of dehydrojuncusol molecule nearly nullified its inhibitory effect on the expression of the pro-inflammatory inducible nitric oxide synthase (iNOS) protein.
Meroditerpenoids from a Formosan soft coral Nephthea chabrolii.
TLDR
Eight new meroditerpenoid-related metabolites, including one naphthoquinone derivative, chabrolonaphthOquinone B, and four tetraprenyltoluquinone-related compounds, chABrolobenzoquinones E-H, were isolated from the organic extract of a Taiwanese soft coral Nephthea chabroii.
Four new nonaoxygenated C18 dibenzocylcooctadiene lignans from Kadsura philippinensis.
Four new nona-oxygenated C18 dibenzocyclooctadiene lignans, kadsuphilins C-F (1-4), were isolated from the EtOAc soluble portion of the alcoholic extract of the aerial parts of Kadsura
Onion Peel Ethylacetate Fraction and Its Derived Constituent Quercetin 4′-O-β-D Glucopyranoside Attenuates Quorum Sensing Regulated Virulence and Biofilm Formation
TLDR
Quercetin 4′-O-β-D glucopyranoside (QGP) was isolated from ONE and its anti-QS potential was confirmed after observing significant inhibition of QS-controlled virulence factors such as violacein, elastase, pyocyanin and biofilm formation in test pathogens.
Proanthocyanidin-rich date seed extract protects against chemically induced hepatorenal toxicity.
TLDR
This study reveals that DTX enhances the recovery from xenobiotics-induced toxicity initiated by free radicals and improves the biochemical parameters by DTX in a dose-dependent manner and confirmed by restoration of normal histological features.
Cytotoxic clerodane diterpenoids from Casearia membranacea.
Bioassay-guided fractionation of the EtOAc extract of Casearia membranacea leaves and twigs afforded three new clerodane diterpenes, caseamembrins M-O (1-3), and the known
Bioactive new withanolides from the cultured soft coral Sinularia brassica.
Suberosols A-D, four new sesquiterpenes with beta-caryophyllene skeletons from a Taiwanese gorgonian coral Subergorgia suberosa.
Four new beta-caryophyllene-derived sesquiterpenes alcohols, suberosols A (1), B (2), C (3), and D (4), along with two known beta-caryophyllene-derived sesqueterpene ketones, buddledins C (5) and D
...
...