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Since the first identification of an association between mutations in the connexin26 (Cx26) gene and autosomal recessive non-syndromic deafness it has been shown that several mutations in this gene cause recessive, sporadic, and dominant non-syndromic deafness. Three novel mutations in the Cx26 gene were identified in four of 20 Japanese families with(More)
OBJECTIVES The aim of the present study was to determine whether there are dialectal and gender-related differences in nasalance scores for normal Japanese speakers. MATERIALS Sixty-eight volunteers consisting of 31 males (age 23.8+/-2.0) and 37 females (age 23.2+/-2.5) were included in this study. They had no diseases affecting speech, and lived in the(More)
OBJECTIVE The purpose of this study was to explore the possibility of using Lyapunov exponents (LE) to evaluate the voice and speech in cleft palate (CP) patients. SUBJECTS AND METHODS Fifty healthy adults (25 males and 25 females) and 17 adult patients (10 males and 7 females) with repaired CP, who had no hypernasality, were enrolled. Five Japanese(More)
OBJECTIVES The aim of this study was to apply a novel method to the analysis of lip motion in patients with bilateral cleft lip and palate before and after lip repair with cross-lip flaps, and to compare lip motion between the patients and healthy volunteers. METHODS Two 17-year-old bilateral cleft lip patients (one male and one female) who underwent lip(More)
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