Astrid Klocke

Learn More
Nuclear factor of activated T-cells (NFAT) and NF-kB pathway associated processes are involved in the pathogenesis of various inflammatory disorders, for example, periodontal disease. The activation of these pathways is controlled by the regulator of calcineurin 1 (RCAN1). The aim of this study was to elucidate the role of RCAN1 in periodontal disease.(More)
BACKGROUND Plasminogen deficiency is a rare autosomal recessive disease, which is associated with aggressive periodontitis and gingival enlargement. Previously described treatments of plasminogen deficiency associated periodontitis have shown limited success. This is the first case report indicating a successful therapy approach consisting of a non-surgical(More)
This prospective study was designed to measure muscle activity with lip bumper treatment. Surface electromyography was used to measure upper and lower lip activity with and without the appliance in place. Measurements were taken on a sample of 25 adolescent patients (age range, 10 to 17 years) before and after 12 months of lip bumper treatment. Recordings(More)
  • 1