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PURPOSE It is well known that individuals with mental retardation (MR), especially those with Down syndrome (DS), have low maximal heart rates (MHR). We evaluated the ability to predict MHR in individuals with MR and DS in comparison with persons without MR. METHODS Subjects completed a maximal exercise test on the treadmill with metabolic and HR(More)
BACKGROUND Stroke carries a poor long-term prognosis for death and disability. There are few acute treatments that reduce death and disability after stroke. The ongoing international, multicenter, randomized, placebo-controlled, double-blind CHIMES trial is currently testing the hypothesis that a 3-month course of the traditional Chinese medicine MLC601(More)
BACKGROUND AND PURPOSE The Efficacy of Nitric Oxide in Stroke (ENOS) trial found that transdermal glyceryl trinitrate (GTN, a nitric oxide donor) lowered blood pressure but did not improve functional outcome in patients with acute stroke. However, GTN was associated with improved outcome if patients were randomized within 6 hours of stroke onset. METHODS(More)
RATIONALE The clinical effects of neuroprotective and/or neurorestorative therapies may vary according to location and size of the ischemic injury. Imaging techniques can be useful in stratifying patients for trials that may be beneficial against particular ischemic lesion characteristics. AIM To test the hypothesis that the efficacy of NeuroAiD compared(More)
This prospective population-based study, involving 4,120 births at the Maternity Unit, Teaching Hospital Kandy, in the years 2008 and 2009, was undertaken to determine the mean birth weight of the newborns in the Central Province, Sri Lanka. The mean birth weight of 2,854 g was found to be equivalent with those calculated from several earlier studies. The(More)
INTRODUCTION The therapeutic effect of domperidone on abdominal pain-predominant functional gastrointestinal diseases (AP-FGIDs) was assessed on children in 5-12 year age group at the Gastroenterology Research Laboratory of Faculty of Medicine, University of Kelaniya, Sri Lanka. METHODS Children fulfilling Rome III criteria for AP-FGIDs were recruited(More)
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