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Progesterone plays a key role in ovarian cycle-related synaptic plasticity and neuronal excitability. Progesterone receptors (PRs), which mediate the cellular actions of progesterone, are expressed in the hippocampus and other limbic regions, but their functional significance remains unknown. Here, we report a novel role of PRs as crucial mediators in the(More)
OBJECTIVE To study the oxygen saturation profile in normal Asian Indian eyes. DESIGN A cross sectional prospective study. SUBJECTS Ninety eight consecutive patients presenting to our hospital with best corrected distance visual acuity (BCVA) of 20/20 and a normal ophthalmic examination were included in the study. Patients having any ocular or systemic(More)
PURPOSE To study the oxygen-saturation profiles in RP and macular dystrophies and compare them with age-matched healthy controls. METHODS In a cross-sectional prospective study, 62 subjects with RP, 23 with macular dystrophies, and 78 controls were enrolled, and retinal oximetry was performed with the Oxymap T1 retinal oximeter. The images were analyzed(More)
Fluorescein angiography (FFA) has been the gold standard to understand, diagnose and treat retinal disorders. However, being an invasive procedure it has several limitations including adverse drug reactions. Hence, noninvasive tests that can be repeated during the course of the disease are the need of the hour. The aim of our study was to compare images of(More)
Acute retinal pigment epithelitis (ARPE), also known as Krill's disease, was first described by Krill and Deutman in 1972 as a bilateral, benign, self limited disease [1]. There are many recent reports [2-5]. That describes the Spectral Domain Optical Coherence Tomography (SD-OCT) findings in ARPE. Lesions of the RPE, inner and outer segments of(More)
Retinal oximetry in bilateral optic disc edema after accidental minoxidil ingestion Aim: To study the oximetry changes in bilateral optic disc edema Methods: A 56 year old man, presenting with painless, bilateral, simultaneous visual loss and a history of accidental ingestion of topical Minoxidil 2% 20 days before presentation; diagnosed to have bilateral(More)
Rhinosporidium seeberi , till recently known as a fungus, has been reclassified as a protistan parasite. It infects humans and many animal species. The authors describe a rare case of oculosporidiosis with involvement of the lacrimal sac exhibiting features of idiopathic orbital inflammatory disease in a young male patient. Clinical features,(More)
A comparative analysis of different conservative modes of therapy for lymphoedema, largely of Filarial origin, was conducted in a trial therapy unit in Chengalpattu, a Filarial endemic district in Tamil Nadu. Results were compared using a single chambered intermittent pneumatic compression pump, heat therapy, and interferential therapy machines. The results(More)
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