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Antioxidant and hepatoprotective activity of Fagonia schweinfurthii (Hadidi) Hadidi extract in carbon tetrachloride induced hepatotoxicity in HepG2 cell line and rats.
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Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage
TLDR
The optimized transfersomes were found to increase the cell viability and reduce the lipid peroxidation, intracellular ROS and expression of MMPs in HaCaT cells, which underline the potential application of the developed transfersomes in sunscreen cream/lotions for improvement of UV radiation-protection along with deriving antioxidant and anti-aging effects.
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Evaluation of antioxidant, in vitro cytotoxicity of micropropagated and naturally grown plants of Leptadenia reticulata (Retz.) Wight & Arn.-an endangered medicinal plant.
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Antitumor activity of Hypericum hookerianum against DLA induced tumor in mice and its possible mechanism of action
TLDR
Administration of the methanol extract not only increased the survival of animals with ascites tumor, decreased the body weight induced by the tumor burden and reduced the packed cell volume and viable tissue cell count, but also altered many hematological parameters changed during tumor progression indicating the potent antitumor nature of the extract.
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Molecular mechanisms underlying gliomas and glioblastoma pathogenesis revealed by bioinformatics analysis of microarray data
TLDR
To identify key genes associated with gliomas and glioblastoma and to explore the related signaling pathways, the GeneTrail2 1.5 tool was used to identify potentially enriched biological processes among the DEGs using gene ontology (GO) terms.
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Antitumor activity and antioxidant status of the methanol extract of Careya arborea bark against Dalton's lymphoma ascites-induced ascitic and solid tumor in mice.
TLDR
The methanol extract of Careya arborea Roxb bark given orally to mice at the dose of 250 or 500 mg/kg body weight for 10 days caused significant reduction in percent increase in body weight, packed cell volume, and viable tumor cell count when compared to the mice of the DLA control group.
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IN VITRO CYTOTOXICITY OF CARALLUMA SPECIES BY MTT AND TRYPAN BLUE DYE EXCLUSION
TLDR
The extracts were found to be moderately toxic and showed dose dependent response and the toxicity of a plant has to be studied for further exploration of various biological activities.
The cytotoxic activity of the total alkaloids isolated from different parts of Solanum pseudocapsicum.
TLDR
The total alkaloid fraction of leaves was found to be the most potent and the HT-29 cell line was the most sensitive to the fractions, which merit further investigations to identify the active constituents in animal models.
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In vitro cytotoxic properties of Grewia tiliaefolia bark and lupeol
Evaluation of in vitro toxicity of Rumalaya liniment using mouse embryonic fibroblasts and human keratinocytes
TLDR
It could be concluded that Rumalaya liniment could be safer to skin due to their low cytotoxicity as compared with CS.
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