Ashley Pretorius

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The demand for antimicrobial peptides (AMPs) is rising because of the increased occurrence of pathogens that are tolerant or resistant to conventional antibiotics. Since naturally occurring AMPs could serve as templates for the development of new anti-infectious agents to which pathogens are not resistant, a resource that contains relevant information on(More)
Cancer is a class of diseases, classified by the organ of origin and characterized by uncontrollable cell growth. Our focus is on prostate cancer (PC) which starts in the prostate and is generally a walnut-sized gland located below the bladder. Approximately 4500 males in South Africa are diadnosed annually, thus making it the second most common cause of(More)
Background: The 2 50 k Da r etinoblastoma bi nding pr otein 6 (RBBP6) was cloned over a decade ago and was found to bind both the p53 and Rb1 tumor s uppressor proteins. In a ddition, R BBP6 has be en a ssociated with multiple b iological f unctions, s uch a s m itosis, m RNA p rocessing, tr anslation and ubiquitination. Objectives: In the current study, an(More)
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