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There is increasing, although largely indirect, evidence that neurotrophic factors not only function as target-derived survival factors for projection neurons, but also act locally to regulate developmental processes. We studied the expression of ciliary neurotrophic factor (CNTF) and the CNTF-specific ligand-binding alpha-subunit of the CNTF receptor(More)
  • Andrea Macrina, I Buckley, G Iori, A Lökka, M Pistorius, W Shaw +59 others
  • 2006
An Information-Based Framework for Asset Pricing: X-Factor Theory and its Applications. This thesis presents a new framework for asset pricing based on modelling the information available to market participants. Each asset is characterised by the cash flows it generates. Each cash flow is expressed as a function of one or more independent random variables(More)
Effects of ciliary neurotrophic factor (CNTF) on photoreceptor development in dissociated cultures of embryonic chick and newborn rat retina were studied using opsin immunoreactivity to characterize photoreceptor differentiation. In the presence of CNTF, the number of photoreceptors was increased by up to 200% in chick cultures, but was reduced by 82-99% in(More)
The development of photoreceptors in the mammalian retina is thought to be controlled by extrinsic signals. We have shown previously that ciliary neurotrophic factor (CNTF) potently inhibits photoreceptor differentiation in cultures of rat retina. The present study analyzes which developmental processes are affected by CNTF. Rod differentiation as(More)
BACKGROUND Neurokinin-1 receptors (NK1-rs) located on superficial dorsal horn neurons are essential for integration of nociceptive input. Intrathecal injection of substance P-saporin (SP-SAP) leads to local loss of spinal NK1-r (+) neurons suggesting its potential as a therapeutic agent for chronic pain. The authors determined, in a canine model, effects of(More)
  • Andrew Wiese, Yaghoob Farnam, Wesley Jones, Paul Imbrock, Bernie Tao, W Jason Weiss +2 others
  • 2016
(2015). Evaluation of sealers and waterproofers for extending the life cycle of concrete The Joint Transportation Research Program serves as a vehicle for INDOT collaboration with higher education institutions and industry in Indiana to facilitate innovation that results in continuous improvement in the planning, design, construction, operation, management(More)
  • B Bhattacharya, M Burmester, Y Hu, E Kranakis, Q Shi, A Wiese
  • 2008
Intrusion detection, area coverage and border surveillance are important applications of wireless sensor networks today. They can be (and are being) used to monitor large unprotected areas so as to detect intruders as they cross a border or as they penetrate a protected area. We consider the problem of how to optimally move mobile sensors to the fence(More)
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