Learn More
OBJECTIVES To determine the reported incidence of acute endophthalmitis following cataract extraction over time and to explore possible contributing factors, such as type of cataract incision. METHODS A systematic review of English-language articles was conducted by performing a broad search of PubMed from 1963 through March 2003 using such terms as(More)
PURPOSE To develop current treatment recommendations for dry eye disease from consensus of expert advice. METHODS Of 25 preselected international specialists on dry eye, 17 agreed to participate in a modified, 2-round Delphi panel approach. Based on available literature and standards of care, a survey was presented to each panelist. A two-thirds majority(More)
OBJECTIVE To estimate the annual incidence rate of presumed endophthalmitis after cataract surgery, evaluate any changes in this rate over time, and examine demographic risk factors for endophthalmitis after cataract surgery. DESIGN Population-based review of Medicare beneficiary claims data. DATA SOURCE Medicare 5% sample beneficiary data files for(More)
PURPOSE To present the first 3 cases of Acanthamoeba keratitis (AK), unresponsive to medical treatment, that were successfully treated with a novel adjunctive therapy using ultraviolet light A (UVA) and riboflavin (B2). DESIGN Interventional case series. PARTICIPANTS Two patients with confirmed AK and 1 patient with presumptive AK, which were all(More)
PURPOSE To determine the most favorable sutureless incision configuration to minimize extraocular fluid inflow after cataract surgery. SETTING The Wilmer Eye Institute, Baltimore, Maryland, USA. METHODS Five fresh human eyes were used in the study. Two 27-gauge needles connected to a saline solution bag and a digital manometer were inserted through the(More)
BACKGROUND The aqueous humor (AH), a liquid of the anterior and posterior chamber of the eye, comprises many proteins with various roles and important biological functions. Many of these proteins have not been identified yet and their functions in AH are still unknown. Recently, our laboratory published the protein database of AH obtained from healthy(More)
PURPOSE To demonstrate the antimicrobial properties of riboflavin/UVA (365 nm) against common pathogens. METHODS One group of bacteria (Pseudomonas aeruginosa [PA], Staphylococcus aureus [SA], and Staphylococcus epidermidis [SE]) was tested by using Kirby-Bauer discs with (1) empty disc (Control - C); (2) riboflavin 0.1% (B2); (3) riboflavin 0.1%(More)
PURPOSE To describe a surgical technique using an artificial anterior chamber to facilitate harvest of Descemet's membrane (DM) and endothelium for corneal endothelial cell transplantation. DESIGN Laboratory investigation. METHODS Corneoscleral buttons of seven human donor eyes were mounted endothelial side up on an artificial anterior chamber. Keeping(More)
BACKGROUND Sutureless clear corneal cataract incisions may be associated with an increased risk of endophthalmitis. OBJECTIVE To assess the degree of ocular surface fluid ingress into the anterior chamber of cadaveric human globes with clear corneal wounds. METHODS Self-sealing clear corneal incisions were created in 4 eyes, and intraocular pressure was(More)
PURPOSE To evaluate the safety and accuracy of a manual microkeratome and an artificial anterior chamber used at high intrachamber pressure to harvest corneal lenticules for lamellar keratoplasty. SETTING Department of Ophthalmology, University of California, Irvine, California, USA. METHODS Forty-seven human eye-bank corneoscleral rims were mounted on(More)