Asha Latha

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SETTING A DOTS clinic in an academic tertiary referral hospital in South India. OBJECTIVE To evaluate the performance of two rapid enzyme-linked immunoassays (EIAs) for the detection of human immunodeficiency virus (HIV) infection in sputum samples of patients with tuberculosis (TB). DESIGN We prospectively recruited 522 consecutive out-patients(More)
SETTING Urine antigen testing is an attractive strategy for the diagnosis of active tuberculosis (TB), but accuracy data are scarce. OBJECTIVE To prospectively evaluate the diagnostic performance of commercial urinary lipoarabinomannan (LAM) antigen testing for active TB among pulmonary and extra-pulmonary TB suspects. DESIGN Prospective blinded(More)
BACKGROUND Vitamin D has immunomodulatory effects that might aid clearance of mycobacterial infection. We aimed to assess whether vitamin D supplementation would reduce time to sputum culture conversion in patients with active tuberculosis. METHODS We did this randomised, double-blind, placebo-controlled, superiority trial at 13 sites in India.(More)
SETTING The microscopic observation drug susceptibility (MODS) assay is a rapid, sensitive, low-cost liquid culture technique. OBJECTIVE To establish the accuracy of MODS for the detection of active pulmonary tuberculosis (TB), and to document the costs and challenges of setting up this assay in a low-income setting. DESIGN Prospective blinded pilot(More)
Trigonella foenum graecum is an Iranian medicinal plant used for the treatment of rheumatoid arthritis and inflammation. The present study was designed to investigate the beneficial outcome of the plant T. foenum graecum on adjuvant-induced arthritis in albino rats. Ethanol extract of T. foenum graecum was tested against Freund's complete adjuvant-induced(More)
BACKGROUND Direct sputum smear microscopy for tuberculosis (TB) lacks sensitivity for the detection of acid fast bacilli. Sputum pretreatment procedures may enhance sensitivity. We did a pilot study to compare the diagnostic accuracy and incremental yield of two short-duration (<1 hour) sputum pretreatment procedures to optimize direct smears among patients(More)
Introduction: The present study has examined the effect of elevated glucose levels on osmotic fragility of erythrocytes. Osmotic fragility determines the rate of hemolysis of erythrocytes. Blood glucose is the sole energy source for erythrocytes. Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemia and has become a major public(More)
Introduction: The extensor digitorum brevis manus (EDBM) muscle is an abnormal muscle originate on the dorsum of the wrist and hand. According to earlier reporters EDBM may originates from various sources like the distal row of the carpal bones or metacarpal bases. The capsule and ligaments of the wrist joint [2] and the dorsum of carpal bones.
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