• Publications
  • Influence
Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study
TLDR
Redefinition of obesity based on waist-to-hip ratio instead of BMI increases the estimate of myocardial infarction attributable to obesity in most ethnic groups. Expand
Association of a human G-protein β3 subunit variant with hypertension
TLDR
A novel polymorphism (C825T) in exon 10 of the gene encoding the p3 subunit of heterotrimeric G proteins (GNB3) is detected, which suggests a significant association of the T allele with essential hypertension. Expand
Obesity prevalence from a European perspective: a systematic review
TLDR
It is observed that obesity has reached epidemic proportions in Europe, with prevalence rates in Central, Eastern, and Southern Europe being higher than those in Western and Northern Europe. Expand
2006 Canadian clinical practice guidelines on the management and prevention of obesity in adults and children [summary]
TLDR
Over the last 20 years, obesity has become the most prevalent nutritional problem in the world, eclipsing undernutrition and infectious disease. Expand
Activation of the peripheral endocannabinoid system in human obesity.
TLDR
The findings support the presence of a peripheral endocannabinoid system that is upregulated in human obesity and increased in mature human adipocytes compared with in preadipocytes and was found in several human tissues. Expand
Epicardial adipose tissue: anatomic, biomolecular and clinical relationships with the heart
TLDR
Echocardiographic assessment of epicardial adipose tissue could be a simple and practical tool for cardiovascular risk stratification in clinical practice and research and could serve as a reliable marker of visceral adiposity. Expand
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects.
TLDR
Subjects with preexisting cardiovascular conditions who were receiving long-term sibutramine treatment had an increased risk ofNonfatal myocardial infarction and nonfatal stroke but not of cardiovascular death or death from any cause. Expand
Weight Loss and the Renin-Angiotensin-Aldosterone System
TLDR
It is suggested that a 5% reduction in body weight can lead to a meaningfully reduced renin-angiotensin-aldosterone system in plasma and adipose tissue, which may contribute to the reduced blood pressure. Expand
The obesity paradox in the elderly: potential mechanisms and clinical implications.
TLDR
The evidence on the relationship between obesity and mortality in the elderly, the definition of obesity in the ageing population, and the need for its treatment in this population is examined. Expand
A Review of Laparoscopic Sleeve Gastrectomy for Morbid Obesity
TLDR
Although LSG is a promising treatment option for patients with morbid obesity, its role remains undefined and it should be considered an investigational procedure that may require revision in a subset of patients. Expand
...
1
2
3
4
5
...