Arvydas Markevicius

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A cell line was established from blood leucocytes of a cow with chronic lymphocytic leukemia. The leucocytes were cultured with conditioned medium (culture fluid of mouse cell line L). In vitro cell transformation was demonstrated by adaptation to permanent growth, modification of cell morphology, the alteration of cell surface phenotype, kinetic behaviour(More)
The toxicity of conventional nitroaromatic explosives like 2,4,6-trinitrotoluene (TNT) is caused by their enzymatic free radical formation with the subsequent oxidative stress, the formation of alkylating nitroso and/or hydroxylamino metabolites, and oxyhemoglobin oxidation into methemoglobin. In order to get an insight into the mechanisms of toxicity of(More)
Low-level copper excess was produced in male BALB/c mice by oral supplementation of copper sulfate solution during a 19-w period. The control Group was supplied with pure drinking water and the 2 experimental Groups with CuSO4.5H2O solutions at 120 mg Cu/L or 300 mg Cu/L, respectively. Compared to the control Group, the copper-dosed animals were slightly(More)
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