Arup Mukherjee

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We present an algorithm for the construction of locally adapted conformal tetrahedral meshes. The algorithm is based on bisection of tetrahedra. A new data structure is introduced, which simplifies both the selection of the refinement edge of a tetrahedron and the recursive refinement to conformity of a mesh once some tetrahedra have been bisected. We prove(More)
Inability to identify weaknesses or to quantify advancements in software system robustness frequently hinders the development of robust software systems. Efforts have been made to develop benchmarks of software robustness to address this problem, but they all suffer from significant shortcomings. This paper presents the various features that are desirable(More)
Gold nanoparticles (Aunp) through biogenetic processes have induced enormous interest for lower toxicity and precise applications. A rapid, one pot synthesis for uniformly sized gold nanoparticles was developed using polyphenolic compound quercetin. Reduction process was followed at low temperatures in a simple bath type sonicator. Nanoparticle plasmon(More)
Abnormal N-heterocyclic carbene (aNHC) adducts of zinc(II) (1) and aluminum(III) (2) were synthesized. The compounds were characterized by NMR spectroscopy and elemental analysis. The solid state structures of these complexes (1 and 2) were determined by single crystal X-ray study. Furthermore, these organozinc and organoaluminum adducts (1 and 2) were(More)
Glycyrrhizic acid has been used in Indian traditional medicine for ages. It is obtained from the root extract of Glycyrrhizaglabra. There is seasonal variation of Glycyrrhizic acid content in the roots of the plant. So a proper method for quantification of the same is necessary from the polyherbal preparation available in the market. A simple, rapid,(More)
In the present work, testosterone-loaded alginate nanocapsules were prepared by in situ nanoemulsification-polymer cross-linking method. Drug loading, particle size (diameter), polydispersity index and zeta potential of these alginate nanocapsules were measured 30.22 ± 1.90%, 34.53 ± 1.72 nm, 0.22 ± 0.04 and -5 mV, respectively. The pharmacokinetic(More)
Silymarin (Sm) is a polyphenolic component extracted from Silybum marianum. It is an antioxidant, traditionally used as an immunostimulant, hepatoprotectant, and dietary supplement. Relatively recently, Sm has proved to be a valuable chemopreventive and a useful antineoplastic agent. Medical success for Sm is, however, constrained by very low aqueous(More)
Visceral leishmaniasis (VL) is a chronic protozoan infection in humans associated with significant global morbidity and mortality. There is an urgent need to develop drugs and strategy that will improve therapeutic response for effective clinical treatment of drug resistant VL. To address this need, andrographolide (AG) nanoparticles were designed with P-gp(More)
In connection to developing non-steroidal estrogen analogs, the present study explores the pharmacophore of triphenylacrylonitriles (Fig. 1) for binding affinity to estrogen receptor using Electrotopological State (E-State) indices of constituting atoms. The analysis shows the efficacy of E-State index in developing statistically acceptable model, which(More)