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Carboxylic acids, activated in situ with DMC, undergo Pd-catalyzed cross-coupling reaction with arylboronic acids to produce unsymmetrical aromatic ketones.
Next Generation Sequencing is a high -throughput DNA sequencing technology based on Non Sangers methods of sequencing. These techniques involve emulsion PCR or bridge PCR for target amplification.… (More)
Glutathione peroxidase (GPx) is a family of protein, which is responsible for eradication of various reactive molecules like H2O2 and other peroxidase helps in protection from oxidative degeneration.… (More)
An operationally simple and scalable three-step one-pot protocol is presented for the synthesis of isatoic anhydrides via N-Boc protection of anthranilic acid derivatives followed by… (More)
Pyruvate dehydrogenase protein is a part of cellular respiration which helps in maintaining glucose and energy level (ATP) in the cells for their normal functioning. Initially it was reported that… (More)
[structures: see text] A seven-step synthesis of (+)-6beta-isovaleryloxylabda-8,13-diene-7alpha,15-diol has been achieved starting from (+)-larixol; this allowed determination of the absolute… (More)
Abstract A phosgene and peroxide-free approach for the synthesis of isatoic anhydrides has been described. The synthesis involves the carbamate formation with Boc anhydride followed by in situ… (More)
Abstract Syntheses of indolin-2-ones and azaindolin-2-ones have been realized. The strategy involves the formation of tosylhydrazone from tosylhydrazine and 2-amino aryl or pyridyl aldehydes/ketones… (More)