Arturo Vargas

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We explore a framework to model the dose response of allosteric multisite phosphorylation proteins using a single auxiliary variable. This reduction can closely replicate the steady state behavior of detailed multisite systems such as the Monod-Wyman-Changeux allosteric model or rule-based models. Optimal ultrasensitivity is obtained when the activation of(More)
The Hermite methods of Goodrich, Hagstrom, and Lorenz (2006) use Her-mite interpolation to construct high order numerical methods for hyperbolic initial value problems. The structure of the method has several favorable features for parallel computing. In this work, we propose algorithms that take advantage of the many-core architecture of Graphics(More)
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