Arturo Galindo-Fraga

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BACKGROUND Mycobacterium tuberculosis (MTB) is one of the leading causes of morbidity and mortality worldwide and infects approximately 1/3 of the human population, but only 10% of all infected individuals will ever develop the disease and half of these may result in a rapid progression to disease during the first 2 years after being infected. On the other(More)
BACKGROUND Influenza-like illnesses (ILI) are estimated to cause millions of deaths annually. Despite this disease burden, the etiologic causes of ILI are poorly described for many geographical regions. METHODS Beginning in April 2010, we conducted an observational cohort study at five hospitals in Mexico City, enrolling subjects who met the criteria for(More)
To the Editor: Vancomycin-resistant Enterococcus (VRE) has become an important nosocomial pathogen because of its rapid spread, limited therapy options, mortality, and the possibility of transfer of vancomycin resistance to other pathogens such as Staphylococcus aureus. Vancomycin-resistant E. faecium (VREF) and E. faecalis were fi rst described in 1988(More)
Zika virus, a flavivirus transmitted to humans by mosquitoes of the genus Aedes, was first described in humans as isolated cases in Africa. Outbreaks have been reported outside that region since 2007, followed by its gradual introduction to different geographical areas. In 2015, Zika virus was detected in Brazil, from where it is rapidly expanding in the(More)
OBJECTIVES To estimate the impact of immune reconstitution inflammatory syndrome (IRIS) on morbidity and mortality in patients starting highly-active antiretroviral therapy (HAART). METHODS A retrospective cohort study of HIV-positive patients starting HAART was conducted at a tertiary care referral center in Mexico City. We estimated the incidence of(More)
OBJECTIVES To study the prevalence, risk factors, outcome, and molecular epidemiology in patients with bacteremia caused by extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae (Kp) (cases), in comparison with patients with bacteremia caused by a susceptible Kp (controls). METHODS This was a retrospective case-control study including(More)
BACKGROUND Carbapenem-resistant Enterobacteriaceae (CRE) infections have emerged as a serious threat to health worldwide. They are associated with increased morbidity and mortality and are capable of silently colonizing the gastrointestinal tract. Because of this, there is great interest to characterize the epidemiology of CRE carriage and acquisition in(More)
INTRODUCTION Delay in appropriate treatment in patients with bacteraemia can increase morbidity, mortality, and health expenditures. We compared the Rapid Direct Test (RDT) designed to detect ESBL-producing gram-negative bacteria (GNB) directly from positive blood cultures bottles, with two conventional ESBL detection tests: Screening and Confirmatory Disk(More)
OBJECTIVE To compare the epidemiology, clinical variables, outcome and molecular characteristics between methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-susceptible S. aureus (MSSA) bloodstream infections (BSI) of patients from a tertiary-care center. METHODS We conducted a five-year retrospective cohort analysis of all patients with at(More)